PEG-MGF — Research Peptide Bulk Supply
Also known as: PEGylated Mechano Growth Factor, PEG-IGF-1Ec, Polyethylene Glycol MGF
PEG-MGF (PEGylated mechano growth factor) — satellite cell research peptide. Wholesale bulk supply, COA/HPLC-MS distributor.
Bulk Catalog Specifications
- Lyophilized powder, ≥98% purity by HPLC-MS (PEG moiety verified by SEC)
- Molecular weight: ~C121H200N42O39 for peptide backbone plus PEG chain
- Available in research vial sizes (5 mg) and bulk aliquot programs
- COA with HPLC and mass spectrometry data per lot
- Cold-chain shipping and storage documentation
- Private-label and white-label bulk inquiry available
Scientific Identifiers
| Sequence | MGF C-terminal E-peptide (24 residues, human 49bp insert frame): YQPPSTNKNT KSQRRKGSTF EEHK (approximate — species-specific variants exist) |
|---|---|
| Residue count | 24 (MGF E-peptide) + PEG polymer |
| Molecular formula | C121H200N42O39 (peptide component only; PEG moiety variable) |
| Molecular weight | Peptide backbone ~2875 g/mol + PEG varies (typically ~5000 Da) |
| PubChem CID | Not applicable (polymer conjugate) |
Research Mechanism Summary
PEG-MGF is a PEGylated form of the 24-amino-acid mechano growth factor (MGF) E-peptide, a C-terminal fragment cleaved from the splice variant IGF-1Ec (the mechano-regulated IGF-1 isoform); the E-peptide alone stimulates muscle satellite cell proliferation and delays their senescence via PI3K/Akt/mTOR and MyoD pathway modulation, independent of the mature IGF-1 domain (https://pubmed.ncbi.nlm.nih.gov/21354439/). MGF promotes satellite cell proliferation while inhibiting differentiation (downregulating MyoD and myogenin), maintaining the stem cell pool for subsequent muscle repair (https://pubmed.ncbi.nlm.nih.gov/22875667/). PEGylation significantly extends the plasma half-life of the peptide, making it more suitable for controlled research dosing paradigms in preclinical models (https://pubmed.ncbi.nlm.nih.gov/24253050/).
For Research Use Only. Not for human or veterinary use. Page copy reflects published preclinical and biochemistry literature only and does not constitute dosage, administration, treatment, or therapeutic guidance.
Catalog Context
PEG-MGF is supplied as a research-grade lyophilized peptide catalog item under the Muscle Growth Research Peptides family. PeptideDistro.com lists this entry for qualified research and wholesale buyers; pricing, MOQ, and documentation packets are reviewed during account intake. Page copy is framed exclusively around mechanism literature, molecular identifiers, and bulk catalog specifications.
Wholesale & Documentation
PeptideDistro.com supplies PEG-MGF in research-grade lyophilized format with COA, HPLC, and mass spectrometry data per lot. Pricing, MOQ, and label coordination are reviewed during account intake.