Kisspeptin-10 — Research Peptide Bulk Supply
Also known as: KP-10, Metastin(45-54), YNWNSFGLRF-NH2
Kisspeptin-10 (KP-10, YNWNSFGLRF-NH2) — GPR54 agonist decapeptide. Wholesale bulk, COA/HPLC-MS, private-label distributor.
Bulk Catalog Specifications
- Lyophilized powder, ≥98% purity by HPLC-MS
- Molecular weight: 1302.4 g/mol (decapeptide with C-terminal amide)
- Available in research vial sizes and bulk aliquot programs
- COA with HPLC and mass spectrometry data per lot
- Cold-chain shipping and storage documentation
- Private-label and white-label bulk inquiry available
Scientific Identifiers
| Sequence | Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2 (YNWNSFGLRF-NH2) |
|---|---|
| Residue count | 10 |
| Molecular formula | C63H83N17O14 |
| Molecular weight | 1302.4 g/mol |
| PubChem CID | 25240297 |
Research Mechanism Summary
Kisspeptin-10 is the biologically active C-terminal decapeptide (10 residues) of the KISS1 gene-encoded kisspeptin family; it acts as an endogenous ligand for the kisspeptin receptor (GPR54/KISS1R) on GnRH neurons in the hypothalamus, causing membrane depolarization and increased GnRH neuron firing rates, driving pulsatile GnRH — and thereby LH and FSH — secretion from the anterior pituitary (https://pmc.ncbi.nlm.nih.gov/articles/PMC4063702/). Seminal research identified mutations in GPR54 as causing hypogonadotropic hypogonadism and infertility in both humans and mice, establishing kisspeptin as a master regulator of the hypothalamic-pituitary-gonadal (HPG) axis (https://pubmed.ncbi.nlm.nih.gov/16595713/). KP-10 has been used in human experimental research to acutely stimulate GnRH pulsatility and explore neuroendocrine feedback mechanisms (https://pubmed.ncbi.nlm.nih.gov/38404024/).
For Research Use Only. Not for human or veterinary use. Page copy reflects published preclinical and biochemistry literature only and does not constitute dosage, administration, treatment, or therapeutic guidance.
Catalog Context
Kisspeptin-10 is supplied as a research-grade lyophilized peptide catalog item under the Reproductive & Neuroendocrine Research Peptides family. PeptideDistro.com lists this entry for qualified research and wholesale buyers; pricing, MOQ, and documentation packets are reviewed during account intake. Page copy is framed exclusively around mechanism literature, molecular identifiers, and bulk catalog specifications.
Wholesale & Documentation
PeptideDistro.com supplies Kisspeptin-10 in research-grade lyophilized format with COA, HPLC, and mass spectrometry data per lot. Pricing, MOQ, and label coordination are reviewed during account intake.