Melanotan II — Research Peptide Bulk Supply
Also known as: MT-2, MTII, Melanotan-2, Ac-Nle4-c[Asp5,D-Phe7,Lys10]-α-MSH(4-10)-NH2
Melanotan II (MTII) — cyclic 7-residue melanocortin agonist research peptide. Wholesale bulk supply, COA/HPLC-MS distributor.
Bulk Catalog Specifications
- Lyophilized powder, ≥98% purity by HPLC-MS
- Molecular weight: 1024.2 g/mol (cyclic heptapeptide)
- Available in research vial sizes (3 mg, 10 mg) and bulk aliquot programs
- COA with HPLC and mass spectrometry data per lot
- Cold-chain shipping and storage documentation
- Private-label and white-label bulk inquiry available
Scientific Identifiers
| Sequence | Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-NH2 (cyclic lactam bridge Asp-Lys) |
|---|---|
| Residue count | 7 |
| Molecular formula | C50H69N15O9 |
| Molecular weight | 1024.2 g/mol |
| PubChem CID | 92432 |
Research Mechanism Summary
Melanotan II is a synthetic cyclic lactam heptapeptide analogue of α-MSH with non-selective agonist activity at melanocortin receptors MC1R through MC4R; MC1R activation stimulates melanogenesis in melanocytes via cAMP/PKA/MITF pathways, while MC4R activation in hypothalamic and spinal cord circuits mediates proerectile and sexual behavior effects in animal models (https://pmc.ncbi.nlm.nih.gov/articles/PMC123265/). Clinical research (small trials) documented erection induction in men with erectile dysfunction via melanocortin-mediated neurogenic pathways (https://pubmed.ncbi.nlm.nih.gov/11035391/), and functional neuroimaging studies confirm MC4R agonism modulates sexual brain processing in women with HSDD (https://pubmed.ncbi.nlm.nih.gov/36189794/). The cyclic lactam bridge (Asp5–Lys10) confers conformational rigidity and resistance to proteolytic degradation relative to linear α-MSH.
For Research Use Only. Not for human or veterinary use. Page copy reflects published preclinical and biochemistry literature only and does not constitute dosage, administration, treatment, or therapeutic guidance.
Catalog Context
Melanotan II is supplied as a research-grade lyophilized peptide catalog item under the Melanocortin Research Peptides family. PeptideDistro.com lists this entry for qualified research and wholesale buyers; pricing, MOQ, and documentation packets are reviewed during account intake. Page copy is framed exclusively around mechanism literature, molecular identifiers, and bulk catalog specifications.
Wholesale & Documentation
PeptideDistro.com supplies Melanotan II in research-grade lyophilized format with COA, HPLC, and mass spectrometry data per lot. Pricing, MOQ, and label coordination are reviewed during account intake.