VIP — Research Peptide Bulk Supply
Also known as: Vasoactive Intestinal Peptide, VIP(1-28), PHI co-secreted partner
VIP (vasoactive intestinal peptide, 28 residues) — neuropeptide research supply. Wholesale bulk, COA/HPLC-MS, private-label.
Bulk Catalog Specifications
- Lyophilized powder, ≥98% purity by HPLC-MS
- Molecular weight: 3326.8 g/mol (28 residues)
- Available in research vial sizes (6 mg) and bulk aliquot programs
- COA with HPLC and mass spectrometry data per lot
- Cold-chain shipping and storage documentation
- Private-label and white-label bulk inquiry available
Scientific Identifiers
| Sequence | His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2 |
|---|---|
| Residue count | 28 |
| Molecular formula | C147H237N43O43S |
| Molecular weight | 3326.8 g/mol |
| PubChem CID | 53314964 |
Research Mechanism Summary
VIP is a 28-residue endogenous neuropeptide found in neural, immune, and GI tissue that signals through VPAC1 and VPAC2 G-protein coupled receptors to stimulate cAMP production via Gs; it acts as a potent anti-inflammatory modulator by suppressing LPS-induced TNF-α, IL-6, IL-12, and IL-17A production in macrophages and monocytes while stimulating anti-inflammatory IL-10 (https://pmc.ncbi.nlm.nih.gov/articles/PMC3883350/). VIP also inhibits IL-8/neutrophil chemotaxis (https://pubmed.ncbi.nlm.nih.gov/12589787/), modulates Th17/iTreg balance in autoimmune models, and has been characterized as an antimicrobial peptide with direct bactericidal and LPS-neutralizing activity (https://pmc.ncbi.nlm.nih.gov/articles/PMC6092975/). Its broad distribution across neural, endocrine, and immune compartments makes it a highly researched tool peptide.
For Research Use Only. Not for human or veterinary use. Page copy reflects published preclinical and biochemistry literature only and does not constitute dosage, administration, treatment, or therapeutic guidance.
Catalog Context
VIP is supplied as a research-grade lyophilized peptide catalog item under the Neuropeptide & Cognitive Research Peptides family. PeptideDistro.com lists this entry for qualified research and wholesale buyers; pricing, MOQ, and documentation packets are reviewed during account intake. Page copy is framed exclusively around mechanism literature, molecular identifiers, and bulk catalog specifications.
Wholesale & Documentation
PeptideDistro.com supplies VIP in research-grade lyophilized format with COA, HPLC, and mass spectrometry data per lot. Pricing, MOQ, and label coordination are reviewed during account intake.