Follistatin 344 — Research Peptide Bulk Supply
Also known as: FST-344, Follistatin isoform 344, FST344
Follistatin 344 is a 344-aa myostatin-binding glycoprotein studied for muscle hypertrophy, satellite cell activation, and GDF-8 inhibition in research models.
Follistatin 344 (FST344) is listed for myostatin/activin-pathway research only. PeptideDistro.com does not frame this entry around hypertrophy, performance, or athletic outcomes.
Bulk Catalog Specifications
- Recombinant (E. coli or CHO-expressed)
- Lyophilized
- 344 amino acids (full isoform)
- MW: ~38.7 kDa (recombinant; glycoprotein migrates ~45 kDa on SDS-PAGE)
- Purity ≥95% (HPLC/SDS-PAGE)
- Storage: −80°C long-term
- COA: SDS-PAGE, MS, activity data
Scientific Identifiers
| Sequence | Human follistatin FST344 isoform (alternative splicing of FST gene; includes all 3 FS domains) |
|---|---|
| Residue count | 344 |
| Molecular formula | C1640H2520N428O496 (approx., glycoprotein-derived, varies by glycosylation state) |
| Molecular weight | ~38700 (38.7 kDa recombinant; ~45 kDa native glycoprotein on SDS-PAGE) |
| PubChem CID | Not confirmed as unique CID |
Research Mechanism Summary
Follistatin-344 is the 344-amino-acid isoform of follistatin, a cysteine-rich glycoprotein that binds and neutralizes myostatin (GDF-8, a TGF-β superfamily member) with high affinity, preventing myostatin from engaging its receptors and lifting the inhibitory brake on skeletal muscle growth. Knockout analyses and transgenic overexpression studies demonstrate that follistatin-mediated myostatin blockade results in both myofiber hypertrophy and hyperplasia — muscle size and number increases — consistent with observations in myostatin-null animals. Follistatin also inhibits activins (which share structural similarity with myostatin), but FST344 isoform research shows differential binding compared to the shorter FST317 isoform, particularly regarding gonadotropin regulation, making isoform identification important in research protocol design.
For Research Use Only. Not for human or veterinary use. Page copy reflects published preclinical and biochemistry literature only and does not constitute dosage, administration, treatment, or therapeutic guidance.
Catalog Context
Follistatin 344 is supplied as a research-grade lyophilized peptide catalog item under the Muscle Growth Research Peptides family. PeptideDistro.com lists this entry for qualified research and wholesale buyers; pricing, MOQ, and documentation packets are reviewed during account intake. Page copy is framed exclusively around mechanism literature, molecular identifiers, and bulk catalog specifications.
Wholesale & Documentation
PeptideDistro.com supplies Follistatin 344 in research-grade lyophilized format with COA, HPLC, and mass spectrometry data per lot. Pricing, MOQ, and label coordination are reviewed during account intake.