Epitalon — Research Peptide Bulk Supply
Also known as: Epithalon, Epithalamine, Ala-Glu-Asp-Gly, AEDG tetrapeptide
Epitalon (AEDG) — 4-residue longevity tetrapeptide. Wholesale bulk research supply, COA/HPLC-MS, private-label distributor.
Bulk Catalog Specifications
- Lyophilized powder, ≥98% purity by HPLC-MS
- Molecular weight: 390.35 g/mol (tetrapeptide)
- Available in research vial sizes (20 mg, 50 mg) and bulk aliquot programs
- COA with HPLC and mass spectrometry data per lot
- Cold-chain shipping and storage documentation
- Private-label and white-label bulk inquiry available
- N-acetyl amidate form also available — see catalog variant
Scientific Identifiers
| Sequence | Ala-Glu-Asp-Gly (AEDG) |
|---|---|
| Residue count | 4 |
| Molecular formula | C14H22N4O9 |
| Molecular weight | 390.35 g/mol |
| PubChem CID | 219042 |
Research Mechanism Summary
Epitalon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) originally derived from an extract of the bovine pineal gland peptide complex epithalamin; in cell line models it induces hTERT mRNA expression and telomerase enzyme activity, producing dose-dependent telomere length extension in normal epithelial and fibroblast cells (https://pmc.ncbi.nlm.nih.gov/articles/PMC12411320/). Proposed mechanisms include binding to histone H1 subunits (H1.3/H1.6) to regulate chromatin structure and epigenetic expression patterns, with differential effects observed between normal cells (telomerase upregulation) and cancer cell lines (ALT pathway activation) in recent 2025 research (https://pubmed.ncbi.nlm.nih.gov/40908429/). Original research by Khavinson et al. (2003) established its activity as an epigenetic regulator in somatic cell models (https://pubmed.ncbi.nlm.nih.gov/12937682/).
For Research Use Only. Not for human or veterinary use. Page copy reflects published preclinical and biochemistry literature only and does not constitute dosage, administration, treatment, or therapeutic guidance.
Catalog Context
Epitalon is supplied as a research-grade lyophilized peptide catalog item under the Longevity & Cellular Research Peptides family. PeptideDistro.com lists this entry for qualified research and wholesale buyers; pricing, MOQ, and documentation packets are reviewed during account intake. Page copy is framed exclusively around mechanism literature, molecular identifiers, and bulk catalog specifications.
Wholesale & Documentation
PeptideDistro.com supplies Epitalon in research-grade lyophilized format with COA, HPLC, and mass spectrometry data per lot. Pricing, MOQ, and label coordination are reviewed during account intake.