Cortagen — Research Peptide Bulk Supply
Also known as: AED Peptide, AEDP Peptide, Ala-Glu-Asp-Pro, Brain Cortex Bioregulator
Cortagen (Ala-Glu-Asp-Pro) is a brain cortex-derived tetrapeptide bioregulator studied for neuroprotection, nerve regeneration, and chromatin decondensation.
Bulk Catalog Specifications
- Lyophilized powder
- Purity ≥99% (HPLC)
- Residue count: 4 (tetrapeptide)
- Sequence: Ala-Glu-Asp-Pro
- MW: 399.4 g/mol (approx.)
- Storage: −20°C, desiccated
- COA: HPLC, MS
Scientific Identifiers
| Sequence | Ala-Glu-Asp-Pro (AEDP) |
|---|---|
| Residue count | 4 |
| Molecular formula | C17H27N5O8 |
| Molecular weight | 429.43 g/mol |
| PubChem CID | Not confirmed |
Research Mechanism Summary
Cortagen (Ala-Glu-Asp-Pro) is a synthetic tetrapeptide derived from amino acid analysis of cortexin, a natural brain cortex polypeptide extract, and has been investigated for neuroprotective and neuroregenerative properties. A cDNA microarray study (Golubev et al., 2004) of 15,247 transcripts in mouse heart revealed 234 transcripts with altered expression following Cortagen administration, including ribosomal gene activation and chromatin decondensation in age-compacted DNA. A sciatic nerve injury study reported that Cortagen treatment increased regenerating nerve fiber growth rate by 27% and conduction velocity by 40% in thick myelinated A-fibers, attributed to epigenetic modulation of neural gene expression programs.
For Research Use Only. Not for human or veterinary use. Page copy reflects published preclinical and biochemistry literature only and does not constitute dosage, administration, treatment, or therapeutic guidance.
Catalog Context
Cortagen is supplied as a research-grade lyophilized peptide catalog item under the Peptide Bioregulators (Khavinson) family. PeptideDistro.com lists this entry for qualified research and wholesale buyers; pricing, MOQ, and documentation packets are reviewed during account intake. Page copy is framed exclusively around mechanism literature, molecular identifiers, and bulk catalog specifications.
Wholesale & Documentation
PeptideDistro.com supplies Cortagen in research-grade lyophilized format with COA, HPLC, and mass spectrometry data per lot. Pricing, MOQ, and label coordination are reviewed during account intake.