Pinealon — Research Peptide Bulk Supply
Also known as: EDR Peptide, Glu-Asp-Arg, Pineal Bioregulator, Cytogen-E
Pinealon (Glu-Asp-Arg) is a synthetic tripeptide bioregulator studied for neuroprotection, ROS reduction, and circadian gene expression modulation.
Bulk Catalog Specifications
- Lyophilized powder
- Purity ≥99% (HPLC)
- Residue count: 3 (tripeptide)
- Sequence: Glu-Asp-Arg
- MW: 432.43 g/mol
- Storage: −20°C, desiccated, light-protected
- COA topics: HPLC purity, MS molecular ion confirmation
Scientific Identifiers
| Sequence | Glu-Asp-Arg (EDR) |
|---|---|
| Residue count | 3 |
| Molecular formula | C16H28N6O8 |
| Molecular weight | 432.43 g/mol |
| PubChem CID | Unknown — not confirmed in PubChem as of research date |
Research Mechanism Summary
Pinealon (Glu-Asp-Arg) is a synthetic tripeptide bioregulator hypothesized to penetrate cellular and nuclear membranes due to its small size and directly modulate gene expression rather than acting through classical cell-surface receptors. Preclinical studies in HeLa cell models support nuclear membrane permeation and DNA interaction, with observed reductions in reactive oxygen species accumulation and caspase-3 activity in hypoxic and ischemic stroke models. Research also indicates upregulation of 5-tryptophan hydroxylase expression through proposed epigenetic mechanisms, suggesting modulation of serotonin biosynthesis pathways in cortical cultures.
For Research Use Only. Not for human or veterinary use. Page copy reflects published preclinical and biochemistry literature only and does not constitute dosage, administration, treatment, or therapeutic guidance.
Catalog Context
Pinealon is supplied as a research-grade lyophilized peptide catalog item under the Peptide Bioregulators (Khavinson) family. PeptideDistro.com lists this entry for qualified research and wholesale buyers; pricing, MOQ, and documentation packets are reviewed during account intake. Page copy is framed exclusively around mechanism literature, molecular identifiers, and bulk catalog specifications.
Citations & Sources
- https://en.wikipedia.org/wiki/Pinealon
- https://peptidebiologix.com/pinealon
- https://biotechpeptides.com/2024/11/08/pinealon-peptide-implications-for-neuroprotection-cellular-aging-mechanisms/
- https://www.corepeptides.com/pinealon-peptide-research-in-neuroprotection-cell-vitality-and-cellular-age-related-processes/
Wholesale & Documentation
PeptideDistro.com supplies Pinealon in research-grade lyophilized format with COA, HPLC, and mass spectrometry data per lot. Pricing, MOQ, and label coordination are reviewed during account intake.