LL-37 — Research Peptide Bulk Supply
Also known as: CAP-18, Human Cathelicidin, hCAP-18/LL-37, CAMP peptide
LL-37 (CAP-18) — 37-residue human cathelicidin research peptide. Wholesale bulk supply, COA/HPLC-MS, private-label distributor.
Bulk Catalog Specifications
- Lyophilized powder, ≥98% purity by HPLC-MS
- Molecular weight: 4493 g/mol (37 residues)
- Available in research vial sizes (5 mg) and bulk aliquot programs
- COA with HPLC and mass spectrometry data per lot
- Cold-chain shipping and storage documentation
- Private-label and white-label bulk inquiry available
Scientific Identifiers
| Sequence | Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser |
|---|---|
| Residue count | 37 |
| Molecular formula | C205H340N60O53 |
| Molecular weight | 4493 g/mol |
| PubChem CID | 16198951 |
Research Mechanism Summary
LL-37 is the 37-residue C-terminal fragment of the human cathelicidin precursor hCAP-18; it is the only cathelicidin-family antimicrobial peptide identified in humans and exhibits broad-spectrum activity against bacteria, fungi, and viruses through membrane permeabilization, biofilm disruption, and oxidative stress mechanisms (https://pubmed.ncbi.nlm.nih.gov/41270816/). Beyond antimicrobial activity, LL-37 modulates innate immune responses by neutralizing lipopolysaccharide (LPS), suppressing macrophage pyroptosis (via P2X7 receptor modulation and caspase-1 inhibition), and stimulating neutrophil release of antimicrobial NETs and ectosomes in sepsis models (https://pubmed.ncbi.nlm.nih.gov/32825174/). Its dual antimicrobial and immunomodulatory profile has driven research interest in wound healing, anti-infective, and inflammatory bowel disease contexts.
For Research Use Only. Not for human or veterinary use. Page copy reflects published preclinical and biochemistry literature only and does not constitute dosage, administration, treatment, or therapeutic guidance.
Catalog Context
LL-37 is supplied as a research-grade lyophilized peptide catalog item under the Immune & Antimicrobial Research Peptides family. PeptideDistro.com lists this entry for qualified research and wholesale buyers; pricing, MOQ, and documentation packets are reviewed during account intake. Page copy is framed exclusively around mechanism literature, molecular identifiers, and bulk catalog specifications.
Wholesale & Documentation
PeptideDistro.com supplies LL-37 in research-grade lyophilized format with COA, HPLC, and mass spectrometry data per lot. Pricing, MOQ, and label coordination are reviewed during account intake.