Vilon (Lys-Glu) — Research Peptide Bulk Supply

• Lyophilized powder
• Purity: >99% by HPLC
• Available research vial sizes: 10 mg, 20 mg
• Storage: -20°C, protect from light
• Solubility: Soluble in water
• COA with HPLC and mass spectrometry data provided per lot
• Cold-chain shipping documentation available
• Private-label and white-label bulk inquiry form available

Vilon (L-Lys-L-Glu) is a synthetic dipeptide bioregulator originally isolated from bovine thymalin by Khavinson et al. It operates epigenetically, selectively binding the CHUK gene (encoding an NF-κB pathway kinase) and modulating chromatin accessibility through deheterochromatinization of facultative heterochromatin—reactivating ribosomal RNA genes and promoting protein synthesis in aging immune cells. In irradiation models, Vilon stimulated thymocyte proliferating cell nuclear antigen (PCNA) index from 26% to 37% and supported recovery of thymic cortex architecture. Studies report up to 6-fold reduction in inflammatory cytokine synthesis alongside increased IL-2 expression and CD4/CD5 upregulation on thymic cells, indicating T-helper cell differentiation (https://www.seekpeptides.com/blog/articles/vilon-peptide-benefits). The dipeptide shows longevity-relevant data: in female rats given subcutaneous injections 5×/week for 12 months, maximum lifespan of the 10% longest-lived controls was extended from 949 to 1048 days and tumor incidence was 1.5-fold lower (https://pubmed.ncbi.nlm.nih.gov/11707921/).

For Research Use Only. Not for human or veterinary use. Page copy reflects published preclinical and biochemistry literature only and does not constitute dosage, administration, treatment, or therapeutic guidance.

• https://pubmed.ncbi.nlm.nih.gov/11707921/
• https://pmc.ncbi.nlm.nih.gov/articles/PMC8365293/
• https://www.corepeptides.com/vilon-peptide-research-into-immune-cell-proliferation-differentiation-and-regulation/