Thymalin — Research Peptide Bulk Supply
Also known as: Thymic polypeptide extract, Timoptin, Polypeptide thymus bioregulator
Thymalin is a thymic polypeptide complex containing EW, KE, and EDP peptides, studied for immune cell regulation. Lyophilized research compound.
Thymalin is a thymic polypeptide complex mixture (EW, KE, EDP and other short peptides) studied for immune cell regulation. Listed strictly as a research-grade mechanistic tool — not the same molecule as Thymulin (FTS) or Thymosin Alpha-1.
Bulk Catalog Specifications
- Lyophilized powder
- Purity: >95% by HPLC (complex mixture)
- Available research vial sizes: 10 mg, 20 mg, 25 mg
- Storage: -20°C, protect from light
- Solubility: Soluble in sterile water
- COA with HPLC and mass spectrometry data provided per lot
- Cold-chain shipping documentation available
- Private-label and white-label bulk inquiry form available
Scientific Identifiers
| Sequence | Polypeptide mixture containing EW (Glu-Trp), KE (Lys-Glu), EDP, and other short peptides; MW 500–1500 Da range |
|---|---|
| Molecular formula | N/A |
| Molecular weight | N/A — mixture of short peptides |
Research Mechanism Summary
Thymalin is a polypeptide complex historically extracted from bovine thymic tissue, containing a mixture of short peptides (500–1500 Da) including the dipeptides EW (thymogen/Glu-Trp) and KE (vilon/Lys-Glu), plus the tripeptide EDP. These active components regulate immune cell differentiation, proliferation, and apoptosis through epigenetic mechanisms: the short peptides bind selectively to histones H1/1, H1/3, H2b, H3, and H4, and to specific DNA sequences (TCGA, AACG motifs), thereby modulating gene expression relevant to T-cell maturation, cytokine production (IL-2, IL-3, IL-6, TNF-α), and fibrinolysis (PMC article: https://pmc.ncbi.nlm.nih.gov/articles/PMC8365293/). Organotypic spleen culture studies showed EW, KE, and EDP increased explant growth zone index by 20–50%, stimulated proliferation, and reduced apoptosis by 29–42%. Clinical applications in Russia have focused on secondary immunodeficiency, infection-related immune suppression, and post-chemotherapy hematopoietic support.
For Research Use Only. Not for human or veterinary use. Page copy reflects published preclinical and biochemistry literature only and does not constitute dosage, administration, treatment, or therapeutic guidance.
Catalog Context
Thymalin is supplied as a research-grade lyophilized peptide catalog item under the Immune & Antimicrobial Research Peptides family. PeptideDistro.com lists this entry for qualified research and wholesale buyers; pricing, MOQ, and documentation packets are reviewed during account intake. Page copy is framed exclusively around mechanism literature, molecular identifiers, and bulk catalog specifications.
Wholesale & Documentation
PeptideDistro.com supplies Thymalin in research-grade lyophilized format with COA, HPLC, and mass spectrometry data per lot. Pricing, MOQ, and label coordination are reviewed during account intake.