Tesamorelin — Research Peptide Bulk Supply
Also known as: Egrifta, Trans-3-hexenoic acid-GHRH(1-44), TH9507
Tesamorelin — 44-residue stabilized GHRH analogue research peptide. Wholesale bulk supply, COA/HPLC-MS, private-label distributor.
Tesamorelin (Egrifta) is FDA-approved for HIV-associated lipodystrophy. The page below frames the research-grade mechanism context (GHRH receptor pharmacology, GH pulsatility modeling) only.
Bulk Catalog Specifications
- Lyophilized powder, ≥98% purity by HPLC-MS
- Molecular weight: ~5135 g/mol (44-residue with hexenoyl modification)
- Available in research vial sizes (2 mg, 5 mg) and bulk aliquot programs
- COA with HPLC and mass spectrometry data per lot
- Cold-chain shipping and storage documentation
- Private-label and white-label bulk inquiry available
Scientific Identifiers
| Sequence | [trans-3-hexenoyl]-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu |
|---|---|
| Residue count | 44 |
| Molecular formula | C221H366N72O67S |
| Molecular weight | ~5135 g/mol |
| PubChem CID | 16137828 |
| Note | FDA-approved drug (Egrifta/Egrifta SV); PubChem CID from description tag |
Research Mechanism Summary
Tesamorelin is a synthetic analogue of human GHRH (1-44) with a trans-3-hexenoic acid moiety conjugated to its N-terminus to enhance serum stability; it activates pituitary GHRH receptors to augment both basal and pulsatile GH secretion, increasing mean overnight GH concentrations and downstream IGF-1 production in research subjects without apparent disruption of physiological somatostatin feedback (https://pmc.ncbi.nlm.nih.gov/articles/PMC3038486/). Clinical pharmacology studies demonstrate significant IGF-1 elevation (mean +181 μg/L) after 14-day administration while preserving insulin-stimulated glucose uptake, in contrast to exogenous recombinant GH (https://pubmed.ncbi.nlm.nih.gov/20943777/). It is FDA-approved (Egrifta) for HIV-associated lipodystrophy, making its mechanism one of the best-characterized among synthetic GHRH analogues.
For Research Use Only. Not for human or veterinary use. Page copy reflects published preclinical and biochemistry literature only and does not constitute dosage, administration, treatment, or therapeutic guidance.
Catalog Context
Tesamorelin is supplied as a research-grade lyophilized peptide catalog item under the GH Secretagogue Research Peptides family. PeptideDistro.com lists this entry for qualified research and wholesale buyers; pricing, MOQ, and documentation packets are reviewed during account intake. Page copy is framed exclusively around mechanism literature, molecular identifiers, and bulk catalog specifications.
Wholesale & Documentation
PeptideDistro.com supplies Tesamorelin in research-grade lyophilized format with COA, HPLC, and mass spectrometry data per lot. Pricing, MOQ, and label coordination are reviewed during account intake.