AHK-Cu (Copper Tripeptide-3) — Research Peptide Bulk Supply

• Lyophilized powder
• Purity: >99% by HPLC
• Available research vial sizes: 50 mg, 100 mg, 200 mg
• Storage: -20°C, protect from light and moisture
• Solubility: Soluble in water
• COA with HPLC and mass spectrometry data provided per lot
• Cold-chain shipping documentation available
• Private-label and white-label bulk inquiry form available

AHK-Cu (L-Ala-L-His-L-Lys-Cu2+) is a copper-chelated tripeptide differing from GHK-Cu by one amino acid (alanine replaces glycine). In an in vitro study using human dermal papilla cells, AHK-Cu at 10⁻¹² to 10⁻⁹ M concentrations significantly increased hair follicle elongation (p<0.001) and DPC proliferation (p<0.001), while reducing the pro-apoptotic markers cleaved caspase-3 by 42.7% and PARP by 77.5% (Arch Pharmacal Res, 2007; https://hairgenetix.com/blogs/articles/copper-peptide-ahk-cu-hair-follicle-growth-study-2007). The copper ion facilitates angiogenic signaling through VEGF upregulation and modulates TGF-β1, both relevant to follicle vascularization and androgenetic alopecia models. Fibroblast studies additionally note that AHK-Cu increases collagen type I synthesis and fibroblast viability, consistent with broader copper-peptide extracellular matrix biology (https://biotechpeptides.com/2025/01/06/ahk-cu-peptide-and-epithelial-tissues/).

For Research Use Only. Not for human or veterinary use. Page copy reflects published preclinical and biochemistry literature only and does not constitute dosage, administration, treatment, or therapeutic guidance.

• https://hairgenetix.com/blogs/articles/copper-peptide-ahk-cu-hair-follicle-growth-study-2007
• https://biotechpeptides.com/2025/01/06/ahk-cu-peptide-and-epithelial-tissues/
• https://www.corepeptides.com/peptides/ahk-cu-200mg/